The Asher Orion Group CEO & Co-founder John F. Kalafut, PhD.
“I founded AOG with Charlotte Kalafut to make a tangible difference to those who are pushing the boundaries of improving healthcare.”
John F. Kalafut
CEO & Co-founder
The Asher Orion Group CEO & Co-founder John F. Kalafut's signature.

Improving the quality and accessibility of healthcare.

Our professional backgrounds in healthcare technologies and life sciences combined with the personal experience of living with a chronic illness drives our mission to see clients succeed in improving the quality and accessibility of healthcare.

Team Experience

We are uniquely qualified to assist clients with their technology, product management, regulatory, and market strategy to anticipate and overcome the full spectrum of hurdles across the healthcare ecosystem.

Product & Solution Management

Built Bayer Radiology Informatics Business

Solution Architects for major, multi-year partnership and R&D collaborations

Developed regulatory strategies and clinical validation of multiple products

Led product mgmt. for radiologist & cardiologist workstations deployed in 1,000s of hospitals globally

Management leading high-acuity, software product organization and business

Supported more than 40 awarded SBIR/STTR and NIH grants and contracts.

Clinical Pathway Optimization

Led creation of AI orchestration solution at GE – first inventor on US patent US10957442 with MGH

DICOM and IHE standards participation and experience

Developed stroke innovation program with MGH and Brigham

Cardiovascular pathway deal architecture

Decades in developing performance solutions for health system C-suites

Strategic product marketing lead for AI-enabled decision support solution built in collaboration with Big Pharma

Academic Co-development

AI digital solutions, Chief Scientist

Authors of many peer-reviewed journal articles, conference abstracts and posters

Co-PI on integrated diagnostics grants, NCIMI, and other UK programs

Development of quality management systems

Developed large public-private organizations to spur research, innovation and technology transfer

Worked with over 120+ life science technology start-ups

John F. Kalafut, PhD

Business Development Director

As CEO of AOG, John advises innovators, vendors and providers in artificial intelligence and machine learning in healthcare. He brings to the table market insights, product development guidance, solution architecture and healthcare digital transformation, scientific and clinical development support.

He is the principal inventor or co-inventor on 43 US patents and ~12 pending applications. Many of his inventions are used in practice around the world, across nuclear medicine and radiological agent delivery, diagnostic and interventional cardiology devices, and patient monitoring systems.

Before founding AOG, John was Chief Scientist of Informatics Research at GE Healthcare. His stewardship of an AI-enabled, diagnostic pathway solution led to their first Breakthrough Designation by the US Food and Drug Administration. He led architecture of learning platforms and applications co-created by GE Healthcare and its clinical partners at world-renowned academic health systems, including Mass General Brigham Healthcare and Boston Children’s Hospital. John was instrumental in the founding of the UK’s National Consortium of Intelligent Medical Imaging (NCIMI) and was a co-Principal Investigator on Digital Pathology and Diagnostic (DART).

Prior to GE, he held various development, research and innovation roles across medical device and pharmaceutical organizations. John received a PhD in Electrical/Bioengineering from the University of Pittsburgh, a Master of Engineering in Bioengineering and Computational Neuroscience from the University of Pittsburgh, and a Bachelor’s in Physics and Electrical Engineering from the University of Scranton. 

Our Team

Charlotte Kalafut
COO & Co-founder
Yernar Akim
Business Development Director
Justin Horton

Make medical AI real.

AI and data science are the future. Is medical AI a reality at your organization? We're here to help you.

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